An International Journal for Oncology Research.  

 


August 2010
Volume 12, Number 8
Cover Illustration:
The cover is an artistic depiction of the results described in the paper by tap et.al. wherein a novel, selective BRAF inhibitor is described and its efficacy in the treatment of malignant melanoma is investigated

TABLE OF CONTENTS

Research Article

Hypoxic tumor microenvironments reduce collagen I fiber density
Samata M Kakkad, Meiyappan Solaiyappan, Brian O’Rourke, Ioannis Stasinopoulos, Ellen Ackerstaff, Venu Raman, Zaver M Bhujwalla and Kristine Glunde
Abstract   Full Article

The effect of eicosapentaenoic acid on E-type prostaglandin synthesis and EP4 receptor signalling in human colorectal cancer cells
G Hawcroft, Paul M Loadman, Andrea Belluzzi and Mark A Hull
Abstract And Supplemental Data   Full Article

MDR1 and ERCC1 expression predict outcome of patients with locally advanced bladder cancer receiving adjuvant chemotherapy
Andreas-Claudius Hoffmann, Peter Wild, Christina Leicht, Simone Bertz, Kathleen D Danenberg, Peter V Danenberg, Robert Stöhr, Michael Stöckle, Jan Lehmann, Martin Schuler and Arndt Hartmann
Abstract   Full Article

Pharmacodynamic characterization of the efficacy signals due to selective BRAF inhibition with PLX4032 in malignant melanoma.
William D Tap, Ke Wei Gong, Judy Dering, Yiou Tseng, Charles Ginther, John A Glaspy, Richard Essner, Gideon Bollag, Peter Hirth, Chao Zhang and Dennis J Slamon
Abstract And Supplemental Data   Full Article

Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell lines
Rebecca J McClaine, Aaron M Marshall, Purnima K Wagh and Susan E. Waltz
Abstract   Full Article

Glutamate receptor GRIA3 – target of CUX1 and mediator of tumor progression in pancreatic cancer
Stefanie Ripka, Jan Riedel, Albrecht Neesse, Heidi Griesmann, Malte Buchholz, Volker Ellenrieder, Franz Moeller, Peter Barth, Thomas M Gress and Patrick Michl
Abstract And Supplemental Data   Full Article

Replication Timing Aberrations and Aneuploidy in Peripheral Blood Lymphocytes of Breast Cancer Patients
Helena Grinberg Rashi, Samuel Cytron, Zully Gelman-Kohan, Talia Litmanovitch and Lydia Avivi
Abstract   Full Article

Review Article

SRC: a century of science brought to the clinic
Alexey Aleshin and Richard S Finn
Abstract   Full Article

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