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| Cancer News |
 November 2008 Volume 10, Number 11 |
Cover Illustration: The cover is an artistic depiction of results from the paper by Jones et.al., wherein Prkar1a ablation was shown to induce Schwannomas by suppressing NF protein production |
TABLE OF CONTENTS
Research Article |
| The malignant phenotype of breast cancer cells is reduced by COX-2 silencing. |
| Ioannis Stasinopoulos, Noriko Mori and Zaver M Bhujwalla |
| Abstract Full Article |
| Pathways to tumorigenesis - modeling mutation acquisition in stem cells and their progeny |
| Rina Ashkenazi, Sara N Gentry and Trachette L Jackson |
| Abstract Full Article |
| Recurrent overexpression of c-IAP2 in EBV-associated nasopharyngeal carcinomas : Critical role in resistance to toll-like receptor 3-mediated apoptosis |
| Luc Friboulet, Catherine Durieu, Sandrini Rodriguez, Alex Valent, Sylvie Souquere, Hugues Ripoche, Abdelmajid Khabir, Sai Wah Tsao, Jacques Bosq, Kwok Wai Lo and Pierre Busson |
| Abstract Full Article |
| Involvement of epigenetic mechanisms in the regulation of secretory phospholipase A2 expression in Jurkat leukemia cells |
| Mario Menschikowski, Albert Hagelgans, Heike Kostka, Graeme Eisenhofer and Gabriele Siegert |
| Abstract Full Article |
| The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP |
| Katherine Striedinger, Scott R VandenBerg, Gilson S. Baia, Michael W McDermott, David H Gutmann and Anita Lal |
| Abstract Full Article |
| Tissue-specific ablation of Prkar1a causes Schwannomas by suppressing NF protein production |
| Georgette N. Jones, Chhavy Tep, William H Towns, Georgeta Mihai, Ian D Tonks, Graham Kay, Petra M Schmalbrock, Anat O Stemmer-Rachamimov, Sung Ok Yoon and Lawrence S Kirschner |
| Abstract Full Article |
| Chromosomal instability is associated with higher expression of genes implicated in EMT, cancer invasiveness and metastasis, and lower expression of genes involved in cell cycle checkpoints, DNA repair and chromatin maintenance. |
| Anna Roschke, Oleg K Glebov, Samir Lababidi, Kristen S Gehlhaus, John N Weinstein and Ilan R Kirsch |
| Abstract Full Article |
| p16INK4a expression and absence of B-RAF are independent predictors of chemosensitivity in melanoma tumors |
| Stuart J Gallagher, John F Thompson, James Indsto, Lyndee L Scurr, Margaret Lett, Bo-Fu Gao, Ruth Dunleavy, Graham J Mann, Richard Kefford and Helen Rizos |
| Abstract Full Article |
| Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component |
| Patrick E Corsino, Bradley J Davis, Peter H Norgaard, Nicole N Teoh Parker, Mary Law, William Dunn and Brian K Law |
| Abstract Full Article |
| Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer |
| Kylie L Gorringe, David Choong, Louise H Williams, Manasa Ramakrishna, Anita Sridhar, Wen Qiu, Jennifer L Bearfoot and Ian G Campbell |
| Abstract Full Article |
| Tumor-selective response to antibody-mediated targeting of alphavbeta3 integrin in ovarian cancer |
| Charles N Landen, Tae J Kim, Yvonne G Lin, Will Merritt, Aparna A Kamat, Liz Han, Whitney A Spannuth, Alpa M Nick, nicholas b jennings, Michael S Kinch, David A Tice and Anil K Sood |
| Abstract Full Article |
| Chemotherapy induced apoptosis in a transgenic model of neuroblastoma proceeds through p53 induction. |
| Louis Chesler, David Goldenberg, Rodney Collins, Matt Grimmer, Grace E Kim, Tarik Tihan, Kim Nguyen, Slava Yakovenko, Katherine K Matthay and William A Weiss |
| Abstract Full Article |
| Overexpression of cell-surface cytokeratin 8 in multidrug-resistant MCF-7/MX cells enhances cell adhesion to the extracellular matrix |
| Fang Liu, Zhong Chen, Jinhong Wang, Xiaofeng Shao, Ziyou Cui, Chunzheng Yang, Zhenping Zhu and Dongsheng Xiong |
| Abstract Full Article |
| Golgi Protein GOLM1 is a tissue and urine biomarker of prostate cancer. |
| Sooryanarayana Varambally, Bharathi Laxman, Rohit Mehra, Qi Cao, saravana dhanasekaran, Scott A Tomlins, Jill Granger, Adaikkalam Vellaichamy, Arun Sreekumar, Jianjun Yu, Wenjuan Gu, Ronglai Shen, Debashis Ghosh, Lorinda M Wright, Raleigh D Kladney, Rainer Kuefer, Mark A Rubin, Claus J Fimmel and Arul M Chinnaiyan |
| Abstract Full Article |
| Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma |
| Abraham Schneider, Rania H. Younis and Silvio Gutkind |
| Abstract Full Article |
| PI3K/Akt pathway activation attenuates the cytotoxic effect of methyl jasmonate towards sarcoma cells |
| Uri Elia and Eliezer Flescher |
| Abstract Full Article |
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